Factor V Leiden Mutation and its Impact on Pregnancy Complications
نویسندگان
چکیده
منابع مشابه
Factor V Leiden mutation and its impact on pregnancy complications.
OBJECTIVE The aim of this prospective study was to find the association between the factor V Leiden mutation and adverse pregnancy outcomes. METHODS This study is an analysis of a prospective observational study of the frequency of placenta-mediated complications of factor V Leiden mutation carriers. We compared pregnancy outcomes of 11 women with a heterozygous form of the factor V Leiden mu...
متن کاملThe impact of the factor V Leiden mutation on pregnancy.
A resistance to the anticoagulant activity of activated protein C (APC), most frequently due to a point mutation in the Factor V gene (the Leiden mutation), represents the most common genetic cause of thrombophilia. The Leiden mutation has been significantly related to pregnancy complications associated with hypercoagulation, e.g. deep vein thrombosis during pregnancy (8-fold increased risk), p...
متن کاملFactor V Leiden mutation in pregnancy.
Normal maternal adaptation to pregnancy significantly increases the risk for thrombus formation. Inherited thrombophilias further increase risk for deep venous thrombosis and adverse outcome in pregnancy. Factor V Leiden mutation is the most common inherited thrombophilia, occurring in approximately 5% of the White and 1% of the Black populations. Nurses should be knowledgeable about screening ...
متن کاملRecurrent Pregnancy Loss in a Subject with Heterozygote Factor V Leiden Mutation; a Case Report
Recurrent pregnancy loss is usually defined as the loss of two or more consecutive pregnancies before 20 weeks of gestation, which occurs in approximately 5% of reproductive-aged women. It has been suggested that women with thrombophilia have an increased risk of pregnancy loss and other adverse pregnancy outcomes. Thrombophilia is an important predisposition to blood clot formation and is cons...
متن کاملFactor V Leiden mutation and pregnancy Haemostasis during pregnancy in non-carriers and carriers of factor V Leiden mutation, with special emphasis on placenta-mediated and venous thromboembolic complications and on blood coagulation and brinolysis markers for prediction of complications
Factor V Leiden mutation and pregnancy Haemostasis during pregnancy in non-carriers and carriers of factor V Leiden mutation, with special emphasis on placenta-mediated and venous thromboembolic complications and on blood coagulation and fibrinolysis markers for prediction of complications. Factor V Leiden (FVL) mutation elevates the risk of venous thromboembolism (VTE) in general. During pregn...
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ژورنال
عنوان ژورنال: Acta Medica (Hradec Kralove, Czech Republic)
سال: 2011
ISSN: 1211-4286,1805-9694
DOI: 10.14712/18059694.2016.32